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Siobain Duffy

Siobain Duffy

Postdoctoral Researcher

Email: smd16@psu.edu

Phone: 814-863-6471

Fax: 814-865-9131

Office: 610 Mueller Laboratory

Research

I am interested in understanding how emerging viruses create and maintain genetic diversity and how they adapt to novel environments. I am also interested in how genomic architecture (i.e. RNA or DNA genome, size of genome) and ecological history constrain future evolution. My specific interests include:

Study systems include

Cystoviruses

Geminiviruses (Tomato Yellow Leaf Curl Virus; East African Cassava Mosaic Virus)

ssDNA bacteriophages

Selected publications

Duffy S, Shackleton LA & Holmes EC (2008) Rates of evolutionary change in viruses: patterns and determinants. Nature Reviews Genetics 9, 267-276

Duffy S & Holmes EC (2008) Phylogenetic evidence for rapid rates of molecular evolution in the single-stranded DNA Begomovirus Tomato yellow leaf curl virus into the New World. Journal of Virology 82: 957-965.

Duffy S & Holmes EC (2007) Multiple introductions of the Old World Begomovirus Tomato yellow leaf curl virus into the New World. Applied and Environmental Microbiology 73: 7114-7117.

Duffy S, Burch CL & Turner PE (2007) Evolution of host specificity drives reproductive isolation among RNA viruses. Evolution 61: 2614-2622

Duffy S, Turner PE & Burch CL (2006) Pleiotropic costs of niche expansion in an RNA virus. Genetics, 172: 1-7.

Duffy S & Schaffner DW (2002) Modeling the environmental contamination of apples with Escherichia coli O157:H7. International Journal of Food Microbiology 78: 245-255