Skip masthead and go to navigation, main content or sidebar.

Penn State shield. Click to visit main Penn State website CIDD, the Center for Infectious Disease Dynamics. Click to visit our home page

Search   …this site   …Penn State  

Eric Harvill

Eric Harvill smiling

Associate Professor of Microbiology and Infectious Disease

Email: harvill@psu.edu

Phone: 814-863-8522

Fax:

Office: 125 Henning Building

Research

I investigate how host and pathogen characteristics and host dynamics affect the spread of respiratory infection within individuals and host populations. My group has four main research areas:

Virulence factors

Host immune functions

Genomics

Comparing genomes of closely-related pathogens to investigate important questions such as:

Phylodynamics

CIDD-related teaching

VSc 520: Pathobiology

Literature-based examination of the molecular basis of infectious disease, including the major molecular approaches and techniques, the strengths and weakness of each and  critical analysis of experimental studies. Prerequisite: VSC 420; BIOCH 401 or BIOCH 437

VSc 497: Bacterial pathogenesis

The central themes and critical studies, examined through the primary literature.

» Find more details about or enroll in one of these courses

Study systems include

Bordetella: closely-related subspecies differing in virulence and gene expression (B.pertussis, B.parapertussis & B.bronchiseptica)

Laboratory in-vitro and in-vivo studies (using a mouse model)

Selected publications

Joo J, Gunny M, Cases M, Hudson P, Albert R & Harvill ET (2006) Bacteriophage-mediated competition in Bordetella bacteria. Proc. Roy. Soc. B.

Pilione MR, Agosto LM, Kennett MJ & Harvill ET (2006) CD11b is required for the resolution of inflammation induced by Bordetella bronchiseptica respiratory infection. Cellular Microbiology 8: 758-768

Kirimanjeswara GS, Agosto LM, Kennett MJ, Bjørnstad ON & Harvill ET (2005). Pertussis toxin inhibits neutrophil recruitment to delay antibody-mediated clearance of Bordetella pertussis. J. Clin. Invest. 115: 3594-3601

Wolfe DN, GS Kirimanjeswara & Harvill ET (2005) Clearance of B. parapertussis from the lower respiratory tract requires both humoral and cellular immunity. Infection & Immunity 73: 6508-6513

Bjørnstad ON & Harvill ET (2005). Evolution and emergence of Bordetella in humans. Trends in Microbiology 13: 355-359.

Harvill ET, Lee G, Grippe VK, Merkel TJ (2005). Complement depletion renders C57BL/6 mice sensitive to the Bacillus anthracis Sterne strain. Infection & Immunity 73: 4420-4422

» More publications, from my lab website.