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Angela Luis

Angie Luis

Graduate Student

Email: adl12@psu.edu

Phone: 814-863-1815

Fax: 814-865-9131

Office: 505 ASI

Research

Since hantavirus was first discovered in the US in 1993, the Centers for Disease Control and Prevention have sponsored longitudinal studies on the rodent reservoir host (the deer mouse). These studies have demonstrated a qualitative correlation among environmental variables, population dynamics and incidence of hantavirus in deer mice, and consequent risk of infection in humans.

My research aims to (a) quantitatively describe how environmental factors affect hantavirus dynamics in its reservoir host in Montana; and (b) to create an ecological model which could predict epizootics. Important questions include:

My research is in collaboration with Rick Douglass at Montana Tech of the University of Montana and Jim Mills at the Centers for Disease Control and Prevention.

Study systems

Deer mice (Peromyscus maniculatus)

Sin Nombre Virus

Publications

Luis AD & Hudson PJ (2006). Hibernation patterns in mammals: a role for bacterial growth? Functional Ecology 20: 471-477

Hickman-Miller HD, Bardet W, Gilb A, Luis AD, Jackson KW, Watkins DI & Hildebrand WH (2005). Rhesus macaque MHC class I molecules present HLA-B like peptides. Journal of Immunology 175: 367-375

Hickman HD, Luis AD, Buchli R, Few SR, Sathiamurthy M, VanGundy RS, Giberson CF & Hildebrand WH (2004). Toward a definition of self: proteomic evaluation of the class I peptide repertoire. Journal of Immunology 172: 2944-2952

Luis AD, Hickman HD, Bardet W & Hildebrand WH (2003). Evaluation of MHC class I peptide-source proteins using Western blots and real-time PCR. Human Immunology 64: S23

Hickman HD, Luis AD, Bardet W, Buchli R, Battson CL, Shearer MH, Jackson KW, Kennedy RC & Hildebrand WH (2003). Cutting edge: Class I presentation of host peptides following HIV infection. Journal of Immunology 171: 22-26